Біохімічний склад та фармакологічний потенціал видів роду Arenaria L.
Анотація
Метою роботи було визначення залежності вмісту фенольних сполук, флавоноїдів та антиоксидантної активності видів роду Arenaria L. від ґрунтово-кліматичних умов Нахічеванської Автономної Республіки. Для цього використовували морфологічний аналіз, високоефективну рідинну хроматографію та спектрофотометрію, а отримані дані піддавали статистичній обробці. Основні результати показали, що зразки з чорноземних ґрунтів Шарурського району мали найвищий вміст фенольних сполук (42,5 ± 3,2 мг/г сухої маси) і флавоноїдів (11,8±1,1 мг/г сухої маси), а також високу антиоксидантну активність, зокрема, ІС50 становила 23,3±1,8 мкг/мл, а антиоксидантна ємність антиоксидантного еквіваленту тролоксу (AEAC) досягала 4,2 ± 0,3 ммоль TE/г. Зразки з гірських районів, таких як околиці сіл Гарагуш та Чалхангала Кангарлінського району, показали найнижчі показники: вміст фенольних сполук становив 24,5±2,6 мг/г, флавоноїдів – 6,2±0,5 мг/г, ІС50 – 43,8±3,1 мкг/мл, а AEAC – 2,2 ± 0,2 ммоль TE/г. Встановлено чітку кореляцію між вмістом біологічно активних сполук та хімічним складом ґрунту, зокрема високий вміст азоту (0,25 ± 0,02 %) та фосфору (220 ± 15 мг/кг) сприяв максимальному накопиченню цих сполук. Практичне значення роботи визначається рекомендаціями щодо оптимальних умов культивування Arenaria L. для отримання рослин з високим вмістом антиоксидантів. Отримані результати підкреслюють важливість адаптації агрономічних підходів до конкретних умов навколишнього середовища для максимальної реалізації фармакологічного потенціалу цих рослин
Ключові слова
фенольні сполуки; флавоноїди; антиоксидантна активність; ґрунтово-кліматичні умови; біологічно активні речовини; біорізноманіття
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