CAUSATIVE AGENTS OF PURULENT WOUNDS AT DOGS AND DETERMINATION OF THEIR SENSITIVITY TO ANTIBIOTICS

In the general structure of surgical pathology the traumatism is 42-55% of total of the studied animals. In a section of surgical pathology of a wound make up to 18% of all surgically sick animals for whose becomings infected use of antibacterial drugs is necessary. Uncontrolled and unsystematic use of antibacterial drugs leads to an increase in the resistance of agents of a surgical infection, an increase in pathogenicity, virulence in microorganisms, and the emergence of new mutational forms. It is necessary to carry out bacteriological studies before each appointment of antibiotic therapy. In work results of microbiological researches of originators of purulent wounds at dogs are presented. It is established that the quantity of microorganisms in 1 ml of an exsudate was 10⁷–10⁹ koloniyeobrazuyushchikh of units. Behind kulturalno-morphological and biochemical researches associations of microorganisms were allocated identified as Str. faecalis, Staph. aureus, Staph. epidermidis and E. coli. The most sensitive the mentioned microorganisms appeared to levomycetinum. Zone of a growth inhibition E. coli and Staph. aureus made 15-25 mm, and Staph. epidermidis – 9-15 mm. E. coli was sensitive to tetracyclinum, is weakly sensitive to neomycinum and a doksitsilin and is tolerant to other antibiotics. Str. faecalis – showed insusceptibility to all studied antibiotics. Staph. aureus except sensitivity to levomycetinum showed weak sensitivity to neomycinum, lincomycin and a doksitsilin and insusceptibility to other antibiotics. Staph. epidermidis also showed weak sensitivity to streptomycinum, levomycetinum and lincomycin and insusceptibility to all other specified antibiotics. Thus, the isolated microorganisms from the wound exudate of purulent dog wounds were the least resistant to levomycetin. For treatment of purulent wounds is chosen ointment "Levomekol", the active substance of which is levomitsetin